朱彩霞

朱彩霞 助理研究员
复旦大学基础医学院
医学分子病毒学教育部卫生部重点实验室,
Shanghai, 200032
联系方式:  021-54237099
邮箱：happyzhucx@fudan.edu.cn
网站：http:www.cailabviralcancer.fudan.edu.cn

研究方向:

1.卡波氏肉瘤病毒与巴尔通体引发血管瘤的机制研究。

2.微环境应激与病毒共诱发细胞增殖、抗凋亡和免疫逃避的促癌机理。

经历背景:

2002.09-2006.07    山东农业大学动物科技院      学士

2006.09-2009.07    山东农业大学动物科技院      硕士

2009.09-2012.09    上海交通大学农业与生物学院  博士

2012.12-                 复旦大学上海医学院    助理研究员

个人简介:

朱彩霞，先后获山东农业大学预防兽医学学士与硕士学位、上海交通大学生物医学工程博士学位。2012年博士毕业后在复旦大学医学分子病毒学教育部卫生部重点室作为助理研究员工作至今。近五年里共发表了SCI论文17篇，多次参加了国内国际学术研讨会（如微生物与感染研讨会、病毒性肝炎研讨会、卡波氏疱疹病毒国际会议等）。申请者近五年内在国际专业权威杂志J Infectious Diseases、PLoS Pathogens、J Virol、J Clin Virol和Virus Res等共发表SCI论文17篇，其中以第一作者发表SCI论文7篇，第二作者发表4篇，并应邀以第一作者发表综述1篇。现担任国际期刊Virus Research、J Cellular Biochem等杂志的稿件评委。

发表文章：

专著

朱彩霞，蔡启良。缺氧信号对卡波济肉瘤病毒感染诱癌的作用。《微生物与感染研究荟萃》，闻玉梅、袁正宏主编，复大大学出版社2014年1月第一版。

论文

1.Zhang L*, Zhu C*, et al. Inhibition of KAP1 enhances hypoxia-induced Kaposi’s sarcoma-associated herpesvirus reactivation through RBP-Jk. Journal of Virology, 2014, 88(12):6873-84 (*并列第一作者) IF=5.605

2.Zhu C, Bai Y, et al. Depolymerization of Cytokeratin Intermediate Filaments Facilitates Intracellular Infection of HeLa Cells by Bartonella henselae. Journal of Infectious Diseases. 2013, 207(9):1397-1405.  IF=5.848 （关于本研究成果的新闻报道: http://www.agri.sjtu.edu.cn/show.aspx?info_lb=539&flag=288&info_id=3174）

3.Zhu C, Yuan C et al. Staining of Bartonella henselae with carboxyfluorescein diacetate succinimidyl ester for tracking infection in erythrocytes and epithelial cells, J Microbiol Methods. 2012, 89 (2):102-6.  IF=2.018

4.Zhu CX,Yuan CL,Cui L,Yu Y,Liu ZW,A R,Zhao W,Hua XG. Molecular detection of Torque teno sus virus from tissues samples of sick pigs in China, Virus Res.2012 May; 165 (2):225-30. (IF=2.905)

5.Zhu C,A R,Yuan C,Yu Y, Cui L, Tang SD, Liu Z, Zhao W, Hua X. Molecular detection of Torque teno mini virus (TTMV) in China, Virus Genes. 2012 Mar 7. (IF=1.693)

6.Zhu C, T.L. Shan, et al. Molecular detection and sequence analysis of feline Torque teno virus (TTV) in China. Virus Res. 2011, 156:13–16.  IF=2.905

7.Zhu C, Cui L, et al. Porcine torque teno virus infections in China. J Clin Virol. 2010, 48(4):296-8.  IF=4.023

8.Zhang L，Zhu C，Cai Q* (2014) . Advances in the pathogenesis of hypoxia signaling mediated by human oncogenic virus, J Microbe Infect, 1(1):16-23（特邀综述）

9.Cai Q*, Cai S, Zhu C, Verma SC, Choi JY, Robertson ES (2013). A SUMO2-interacting motif within LANA is essential for KSHV latency. PLoS Pathogens, 9(10):e1003751.  影响因子IF: 9.2  *通讯作者（关于本研究成果的新闻报道: http://medicine.fudan.edu.cn/show.aspx?info_lb=20&flag=13&info_id=794）

10.Yuan C,Zhu C,Wu Y,Pan X,Hua X. Bacteriological and Molecular Identification of Bartonella Species in Cats from Different Regions of China, PLoS Negl Trop Dis. 2011 Sep; 5(9):e1301. (IF=4.752)

11.Congli, Yuan; Caixia, Zhu; Xiuguo, Hua. Bartonella henselae infection and its effects on human health, Review in Medical Microbiology, 2011, 22 (4):67–72. (IF=0.545)

12.Congbin Yao, Caixia Zhu, XueYin Pan, Xiuguo Hua and Congli, Yuan. A review of the prevalence of emerging Bartonellosis in humans and animals in China, African Journal of Microbiology Research, 2011, 5(25), pp. 4248-4252. (IF=0.528)

13.Yu Y,Shan T,Zhu S,Zhu C,Hua X,Wang C. Prokaryote expression of HPeV-1 VP1 protein, production of VP1 polyclonal antibody and the development of an ELISA. J Virol Methods. 2012 Jun; 182 (1-2):56-61. (IF=2.139)

14.Zhao W, Zhu AL, Yu Y, Yuan CL,Zhu CX, Lan DL, Yang ZB, Cui L, Hua XG. Segmentation expression of capsid protein as an antigen for the detection of avian nephritis virus infection in chicken flocks. J Virol Methods. 2012 Jan; 179(1):57-61. (IF=2.139)

15.Zhao W, Zhu AL, Yuan CL, Yu Y,Zhu CX, Lan DL, Yang ZB, Cui L, Hua XG. Detection of astrovirus infection in pigeons (Columbia livia) during an outbreak of diarrhoea. Avian Pathol. 2011 Aug; 40(4):361-5. (IF=1.654)

16.Zhao W, Zhu AL, Yu Y, Yuan CL,Zhu CX, Yang ZB, Cui L, Hua XG. Complete sequence and genetic characterization of pigeon avian nephritis virus, a member of the family Astroviridae. Arch Virol. 2011 Sep; 156(9):1559-65. (IF=2.209)

17.Zhu AL, Zhao W, Yin H, Shan TL,Zhu CX, Yang X, Hua XG, Cui L. Isolation and characterization of canine astrovirus in China. Arch Virol. 2011 Sep; 156(9):1671-5. (IF=2.209)

专利申请和授权

蔡启良，朱彩霞，蔡山山(2013)。抗卡波氏肉瘤疱疹病毒的疫苗药物SIM靶点。申请专利号20131043187.0.   *通讯作者

科研项目：

主持上海科委扬帆计划：磷酸化STAT6在病毒诱发人恶性淋巴瘤中的致病作用， 2015-2017

参与国家自然科学基金: 缺氧信号介导卡波氏肉瘤病毒致病作用及机制研究, 2015-2018

参与教育部“新世纪优秀人才”计划：血管皮肤瘤中KSHV病毒与巴尔通体致病相关性研究, 2014-2016

参与国家重大基础研究“973”项目子课题：HBV和HIV入侵靶细胞的机制, 2014-2016

参与上海教委科研创新重点项目：抑癌蛋白VHL对KSHV相关肿瘤恶性行为的影响, 2013-2015

参与国家自然科学基金:VHL介导的HIF信号通路对HPV相关肿瘤恶性行为的影响, 2009-2012

学术会议报告：

1)17th International Workshop on Kaposi’s Sarcoma Associated Herpesvirus (KSHV) and Related Agents. July 25-28, 2014. Title: Constitutive STAT6 activation in Primary Effusion Lymphoma北京，大会报告